Christian Stolte - Keith Stolte (17/22 episodes).

Muse Watson - Charles Westmoreland (18/22 episodes).

Frank Grillo - Nick Savrinn (18/22 episodes).

Phillip Edward Van Lear - Louis Patterson (19/22 episodes).

Stacy Keach - Henry Pope (20/22 episodes).

Rockmond Dunbar - Benjamin Miles 'C-Note' Franklin (16/22 episodes).

Robert Knepper - Theodore 'T-Bag' Bagwell (19/22 episodes).

Paul Adelstein - Paul Kellerman (19/22 episodes).Sarah Wayne Callies - Sara Tancredi (22/22 episodes).Wade Williams - Brad Bellick (22/22 episodes).Peter Stormare* - John Abruzzi (17/22 episodes).Marshall Allman - Lincoln 'LJ' Burrows Jr (11/22 episodes).Amaury Nolasco - Fernando Sucre (22/22 episodes).Robin Tunney - Veronica Donovan (22/22 episodes).

Wentworth Miller - Michael Scofield (22/22 episodes).Dominic Purcell - Lincoln Burrows (22/22 episodes).

Paul Adelstein and Robert Knepper were credited as guest stars before episode 3 Peter Stormare was credited as a guest star after episode 13 and Rockmond Dunbar was credited as a guest star before episode 14.

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